Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694635 | 0.89 | HTR1B (0.53) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10694997 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL10694297 | 0.82 | HTR1B (0.55) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10693012 | 0.81 | HTR1B (0.42) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10692959 | 0.80 | HTR1B (0.56) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10693265 | 0.77 | SLC6A4 (0.49) | HTR1BKDM4EALDH1A1 | |
| SCHEMBL10695962 | 0.76 | HTR1B (0.62) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10691295 | 0.75 | HTR1B (0.60) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10692799 | 0.75 | HTR1B (0.60) | HTR1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10691756 | 0.75 | HTR1B (0.60) | HTR1BKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |