Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 5/20 | 0.33 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435343 | 0.84 | GRIA4 (0.45) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL30943788 | 0.83 | TSHR (0.41) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL15435180 | 0.79 | GRIA4 (0.42) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL8762246 | 0.73 | TSHR (0.48) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL8545831 | 0.72 | TSHR (0.46) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL4450297 | 0.72 | HRH1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL12971364 | 0.70 | TSHR (0.44) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL11492811 | 0.68 | GRIA4 (0.41) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL292572 | 0.68 | TSHR (0.52) | TSHRGRIA4LMNATYRTP53 | |
| SCHEMBL8053565 | 0.67 | GRIA4 (0.47) | TSHRGRIA4LMNATYRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253501-A2 | N-disubstituted cycloalkylmethyl amines useful as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |