Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899110 | 0.93 | MAOA (0.67) | MAOAMETAP1S100A4ITGA1CES1 | |
| SCHEMBL10691369 | 0.90 | METAP1 (0.71) | MAOAMETAP1S100A4CES1HSP90AA1 | |
| SCHEMBL6905130 | 0.89 | METAP1 (0.65) | MAOAMETAP1S100A4ITGA1CES1 | |
| SCHEMBL1921628 | 0.88 | KDM4E (0.59) | MAOAMETAP1S100A4ITGA1CYP1A2 | |
| SCHEMBL11145884 | 0.86 | MAOA (0.57) | MAOAMETAP1S100A4ITGA1CES1 | |
| SCHEMBL4135475 | 0.85 | CES1 (0.61) | MAOAMETAP1S100A4CES1TDP1 | |
| SCHEMBL5021694 | 0.82 | MAOA (0.82) | MAOACES1BCHECYP1A2KDM4E | |
| Anthrone SCHEMBL1527782 | 0.82 | MAOA (1.00) | MAOACES1BCHECYP1A2KDM4E | |
| Anthrone SCHEMBL29448801 | 0.82 | MAOA (1.00) | MAOACES1BCHECYP1A2KDM4E | |
| Anthrone SCHEMBL29357010 | 0.82 | MAOA (1.00) | MAOACES1BCHECYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |