Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.71 |
| ▸ | S100A4 | P26447 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905130 | 0.94 | METAP1 (0.65) | METAP1S100A4MAOAMAOBAHR | |
| SCHEMBL10694841 | 0.90 | MAOA (0.67) | METAP1S100A4MAOAHSP90AA1CES1 | |
| SCHEMBL1512750 | 0.87 | METAP1 (0.67) | METAP1S100A4MAOAMAOBAHR | |
| SCHEMBL2601324 | 0.86 | METAP1 (0.60) | METAP1S100A4AHRHSP90AA1F7 | |
| SCHEMBL29572171 | 0.85 | METAP1 (0.57) | METAP1S100A4AHRCMA1HSP90AA1 | |
| SCHEMBL1922789 | 0.85 | METAP1 (0.57) | METAP1S100A4AHRCMA1HSP90AA1 | |
| SCHEMBL6899110 | 0.82 | MAOA (0.67) | METAP1S100A4MAOAMAOBCES1 | |
| SCHEMBL10692517 | 0.82 | METAP1 (0.56) | METAP1S100A4MAOAMAOBAHR | |
| SCHEMBL6906371 | 0.80 | METAP1 (0.54) | METAP1S100A4MAOAMAOBHSP90AA1 | |
| SCHEMBL1029292 | 0.79 | ALDH1A1 (0.59) | METAP1S100A4MAOAMAOBAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044575-A1 | CONSTRAINED BENZHYDRYL SULFONAMIDES AS ANTICANCER AND NEUROPROTECTIVE AGENTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2017-03-16 | — | — | WO | disclosed |
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |