Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337631 | 0.91 | TAAR1 (0.57) | TAAR1FFAR4TDP1L3MBTL1CASP3 | |
| SCHEMBL110045 | 0.88 | IAPP (0.58) | IAPPTAAR1FFAR4TDP1L3MBTL1 | |
| SCHEMBL4659299 | 0.84 | TAAR1 (0.59) | TAAR1FFAR4TDP1L3MBTL1CASP3 | |
| SCHEMBL7507667 | 0.83 | MMP12 (0.54) | TAAR1FFAR4TDP1L3MBTL1HDAC3 | |
| SCHEMBL28910429 | 0.82 | IAPP (0.62) | IAPPTAAR1HDAC6 | |
| SCHEMBL29842802 | 0.81 | ALDH1A1 (0.62) | TAAR1FFAR4CASP3CASP7HDAC3 | |
| SCHEMBL456436 | 0.81 | FFAR4 (0.67) | TAAR1FFAR4THRATHRBCTBP2 | |
| SCHEMBL2027905 | 0.81 | ALDH1A1 (0.62) | TAAR1FFAR4CASP3CASP7HDAC3 | |
| SCHEMBL2436067 | 0.81 | CTBP2 (0.56) | TAAR1TDP1L3MBTL1CASP3CASP7 | |
| SCHEMBL11069047 | 0.81 | KMT2A (0.49) | TAAR1FFAR4TDP1L3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269916-A1 | Saccharin salts of substituted hydroxypropylamines | BAYER AG (DE) | 1988-06-08 | — | — | EP | disclosed |