SCHEMBL10694909

SCHEMBL10694909

Cn1nnnc1COc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 1/20 0.32
HTR2C P28335 1/20 0.32
SYK P43405 1/20 0.32
PPOX P50336 1/20 0.31
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
BRD9 Q9H8M2 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2834367 0.92 KMT2A (0.33) HTR2CPPOXBRD9DHODH
SCHEMBL2841589 0.88 KDM4C (0.40) PPOXDHODH
SCHEMBL6226436 0.87 DHODH (0.30) DHODH
SCHEMBL2835525 0.84 GAA (0.31)
SCHEMBL2833406 0.84 BCAT1 (0.33) PPOX
SCHEMBL2836052 0.83 PDE7A (0.38) PPOXDHODH
SCHEMBL2841004 0.83 PPOX (0.32) PPOX
SCHEMBL10697368 0.82 PPOX (0.33) PPOX
SCHEMBL10577873 0.82 PPOX (0.35) PPOXDHODH
SCHEMBL10574921 0.82 PPOX (0.44) PPOXBRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255047-A1 3-Aryl uraciles and their use as herbicides CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed