SCHEMBL2834367

SCHEMBL2834367

CCn1nnnc1COc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.32
PPOX P50336 2/20 0.31
BRD9 Q9H8M2 1/20 0.31
HTR2C P28335 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2835525 0.93 GAA (0.31) KMT2AGAA
SCHEMBL10694909 0.92 P2RY12 (0.32) PPOXBRD9HTR2CDHODH
SCHEMBL2841589 0.91 KDM4C (0.40) PPOXDHODH
SCHEMBL6226436 0.85 DHODH (0.30) DHODH
SCHEMBL2833216 0.83 KDM4C (0.41)
SCHEMBL2835867 0.82 PPOX (0.31) PPOX
SCHEMBL10574921 0.82 PPOX (0.44) PPOXBRD9
SCHEMBL2836052 0.81 PDE7A (0.38) PPOXDHODH
SCHEMBL2841004 0.80 PPOX (0.32) PPOX
SCHEMBL10697368 0.80 PPOX (0.33) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060025591-A1 New uracils having a herbicidal activity ISEM S.R.L. (IT) 2006-02-02 US claimed
US-7754880-B2 Uracils having a herbicidal activity ISAGRO RICERCA S.R.L. (IT) 2010-07-13 US disclosed
US-20060025591-A1 New uracils having a herbicidal activity ISEM S.R.L. (IT) 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025591-A1 New uracils having a herbicidal activity UNG, DDT, UMPS KMT2A 1729/4885GAA 187/4885PPOX 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.