Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688776 | 0.84 | TAAR1 (0.47) | ADRA2AADRA2BADRA2CTAAR1PDE10A | |
| SCHEMBL10689984 | 0.78 | MAPT (0.44) | MAPTMAPK1HCRTR1TP53ALOX15 | |
| SCHEMBL10688636 | 0.72 | MAPT (0.45) | MAPTMAPK1HCRTR1TP53ALOX15 | |
| SCHEMBL10690155 | 0.72 | ATP4A (0.55) | MAPTMAPK1HCRTR1TP53ALOX15 | |
| SCHEMBL12145159 | 0.72 | MAPT (0.50) | MAPTMAPK1HCRTR1TP53ALOX15 | |
| SCHEMBL10691659 | 0.72 | MAPT (0.50) | MAPTMAPK1HCRTR1TP53ALOX15 | |
| SCHEMBL10694924 | 0.70 | POLB (0.53) | MAPTMAPK1HCRTR1TP53ALOX15 | |
| SCHEMBL10929929 | 0.70 | ADRA2A (0.67) | ADRA2AADRA2BADRA2CTAAR1PDE10A | |
| SCHEMBL956439 | 0.70 | TAAR1 (0.65) | ADRA2AADRA2BADRA2CTAAR1PDE10A | |
| SCHEMBL12145158 | 0.69 | MAPT (0.55) | MAPTMAPK1HCRTR1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |