Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL4303508 | 0.85 | LMNA (0.63) | LMNAALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL28222922 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ATMHCAR2TSHRTDP1 | |
| Bicarbonate SCHEMBL1538407 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ATMHCAR2TSHRTDP1 | |
| SCHEMBL1538408 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ATMHCAR2TSHRTDP1 | |
| SCHEMBL1069759 | 0.78 | LMNA (0.46) | LMNAALDH1A1ATMHCAR2TSHR | |
| Acetic Acid SCHEMBL2136672 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ATMHCAR2TSHRTDP1 | |
| Bicarbonate SCHEMBL28245896 | 0.77 | LMNA (0.44) | LMNAALDH1A1HCAR2TSHRAKR1B1 | |
| SCHEMBL36671 | 0.76 | — | — | |
| SCHEMBL361462 | 0.76 | PAM (0.45) | ALDH1A1ATMHCAR2TSHRTDP1 | |
| SCHEMBL15986332 | 0.75 | HCAR2 (0.39) | LMNAALDH1A1HCAR2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267460-A1 | Transparent polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-18 | — | — | EP | disclosed |