Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5978 | 0.84 | F11 (0.52) | SLC6A2MMP12MMP13F2F11 | |
| SCHEMBL5984 | 0.84 | F11 (0.52) | SLC6A2MMP12MMP13F2F11 | |
| SCHEMBL11115 | 0.78 | — | — | |
| SCHEMBL10282788 | 0.78 | LPL (0.40) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL13313519 | 0.74 | LIPG (0.35) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL12189219 | 0.71 | LPL (0.39) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL10999 | 0.71 | SLC6A2 (0.58) | SLC6A2MMP12MMP13 | |
| SCHEMBL5656 | 0.71 | SLC6A2 (0.58) | SLC6A2MMP12MMP13 | |
| SCHEMBL10867 | 0.71 | SLC6A2 (0.58) | SLC6A2MMP12MMP13 | |
| SCHEMBL6025 | 0.71 | SLC6A2 (0.55) | SLC6A2MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |