SCHEMBL3309054

SCHEMBL3309054

C[SiH2]O[Si](O[SiH2]C)(O[SiH2]C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18094274 0.89 POLB (0.33) ESR1ESR2CA4
SCHEMBL18094265 0.83 KCNH2 (0.31)
SCHEMBL15453122 0.83
SCHEMBL10784166 0.80 ESR1 (0.33) ESR1ESR2CA4
SCHEMBL10695074 0.80 ESR1 (0.33) ESR1ESR2CA4
SCHEMBL182248 0.78 ESR1 (0.37) ESR1ESR2
SCHEMBL250237 0.78 ESR1 (0.37) ESR1ESR2
SCHEMBL11653537 0.76 ESR1 (0.31) ESR1ESR2
SCHEMBL6064639 0.76 ESR1 (0.35) ESR1ESR2
SCHEMBL8734167 0.73 LCK (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100112017-A1 Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics DOW CORNING TORAY COMPANY, LTD. (JP) 2010-05-06 US disclosed
WO-2008032883-A2 COMPOSITION FOR THE PREPARATION OF COSMETICS, COSMETIC, AND METHOD FOR THE PREPARATION OF WATER-CONTAINING COSMETICS DOW CORNING TORAY CO., LTD. (JP) 2008-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100112017-A1 Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics H1-0, DEGS1, MSR1 ESR1 2210/4885ESR2 2180/4885CA4 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.