SCHEMBL182248

SCHEMBL182248

C[SiH2]O[Si](C)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6471969 0.92 ESR1 (0.32) ESR1ESR2
SCHEMBL17456821 0.83 ESR1 (0.32) ESR1ESR2
SCHEMBL250237 0.81 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL8968836 0.80 ESR1 (0.31) ESR1ESR2
SCHEMBL10784166 0.78 ESR1 (0.33) ESR1ESR2
SCHEMBL3309054 0.78 ESR1 (0.33) ESR1ESR2
SCHEMBL10695074 0.78 ESR1 (0.33) ESR1ESR2
SCHEMBL6703907 0.77 ESR1 (0.34) ESR1ESR2
SCHEMBL4781738 0.76 ESR1 (0.33) ESR1ESR2
SCHEMBL6064639 0.74 ESR1 (0.35) ESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1974 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4253478-B1 EPOXY RESIN COMPOSITION AND TRANSPARENT COMPOSITE MATERIAL COMPRISING SAME, AND LAMINATED BOARD GUANGDONG HINNO TECH CO LTD (CN) 2025-04-30 EP claimed
US-12179418-B2 Siloxane additive manufacturing composition SPECTROPLAST AG (CH) 2024-12-31 US claimed
CN-118772837-A Organic silicon sealant, preparation method thereof and photovoltaic module 天合光能股份有限公司 2024-10-15 CN claimed
CN-118290467-A Preparation of siloxane modified imide alicyclic epoxy resin 中山大学 2024-07-05 CN claimed
US-20240132810-A1 Compositions for the Removal of Silicone Deposits NuGeneration Technologies, LLC dba NuGenTec (US) 2024-04-25 US claimed
CN-117534965-A High-temperature-resistant composite rubber roller material and preparation method thereof 安徽时俱新材料科技有限公司 2024-02-09 CN claimed
US-11891592-B2 Compositions for the removal of silicone conformal coatings from a printed circuit board NuGeneration Technologies, LLC (US) 2024-02-06 US claimed
CN-115785676-B Flame-retardant silicone rubber material and preparation method and application thereof 清远市普塞呋磷化学有限公司 2024-02-06 CN claimed
CN-117304222-A Preparation of polysiloxane block modified acrylate polyimide material 中山大学 2023-12-29 CN claimed
EP-4253478-A1 EPOXY RESIN COMPOSITION AND TRANSPARENT COMPOSITE MATERIAL COMPRISING SAME, AND LAMINATED BOARD Guangdong Hinno-Tech Co., Ltd. (CN) 2023-10-04 EP claimed
US-5082735-A PROCESS OF CURING METHYLHYDROSILOXANES DOW CORNING CORPORATION (US) 1992-01-21 US claimed
EP-0440542-A1 Washing composition based on insoluble silicones and a polyoxyalkyleneether carboxylic acid type surfactant and their application in cosmetics and dermatology L'OREAL (FR) 1991-08-07 EP claimed
EP-0424260-A1 Cosmetic use of an aqueous dispersion from organopolysiloxanes and from a cross-linked ammonium acrylate/acrylamide copolymer L'OREAL (FR) 1991-04-24 EP claimed
EP-0398573-A2 Devices featuring silicone elastomers AT&T Corp. (US) 1990-11-22 EP claimed
US-4954597-A ALLYL ESTER, METAL CATALYST DOW CORNING CORPORATION (US) 1990-09-04 US claimed
US-4954401-A Process of curing methylhydrosiloxanes DOW CORNING CORPORATION (US) 1990-09-04 US claimed
US-4912242-A Process for preparing silicon esters DOW CORNING CORPORATION (US) 1990-03-27 US claimed
US-4849172-A Optical sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-18 US claimed
EP-0243116-A2 Optical sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-10-28 EP claimed
US-3942937-A Method of providing durable, slick sliding surfaces on extrusion forming apparatus, and the product thereof GENERAL ELECTRIC COMPANY (US) 1976-03-09 US claimed