Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848672 | 0.81 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8388011 | 0.81 | HTT (0.68) | OPRM1OPRK1MEN1KMT2AHTR6 | |
| SCHEMBL17072027 | 0.81 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28644166 | 0.80 | HDAC3 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL8387376 | 0.80 | HTT (0.67) | OPRM1OPRK1MEN1KMT2AHTR6 | |
| SCHEMBL8540875 | 0.80 | HTR6 (0.54) | OPRM1OPRK1HTR6POLBALDH1A1 | |
| SCHEMBL8540877 | 0.80 | HTR6 (0.54) | OPRM1OPRK1HTR6POLBALDH1A1 | |
| SCHEMBL7782471 | 0.78 | HTR6 (0.53) | OPRM1OPRK1HTR6POLBALDH1A1 | |
| SCHEMBL19000608 | 0.78 | HTT (0.79) | OPRK1MEN1KMT2APOLBMAPT | |
| SCHEMBL18105310 | 0.78 | BCHE (0.73) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791118-A | BACTERICIDES; GRAMNEGATIVE AND -POSITIVE BACTERIA; ANIMAL INFECTIONS; PLANT DISEASES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0216323-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-04-01 | — | — | EP | disclosed |