Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1565063 | 0.84 | HTR1E (0.47) | NPC1RAB9AEPHX1MEN1LMNA | |
| SCHEMBL10694530 | 0.84 | SLC6A3 (0.49) | NPC1RAB9ASLC6A3EPHX1MEN1 | |
| SCHEMBL9780781 | 0.82 | HTR1E (0.61) | SLC6A3MEN1LMNAMAPTHTR1E | |
| SCHEMBL17847165 | 0.81 | POLB (0.46) | NPC1RAB9ASLC6A3EPHX1MEN1 | |
| SCHEMBL9966559 | 0.81 | POLB (0.46) | NPC1RAB9ASLC6A3EPHX1MEN1 | |
| SCHEMBL8875745 | 0.80 | HTR1E (0.63) | SLC6A3MEN1LMNAMAPTHTR1E | |
| SCHEMBL2644996 | 0.80 | HTR1E (0.63) | SLC6A3MEN1LMNAMAPTHTR1E | |
| SCHEMBL14390374 | 0.79 | SLC6A3 (0.63) | SLC6A3 | |
| SCHEMBL1063230 | 0.77 | LMNA (0.41) | SLC6A3EPHX1MEN1LMNAMAPT | |
| SCHEMBL7268591 | 0.77 | CACNA1B (0.43) | MEN1LMNAMAPTHTR1EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272580-A2 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1988-06-29 | — | — | EP | disclosed |