Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160736 | 0.91 | PDE5A (0.46) | PDE5ATLR8PDE4APDE4BPDE4C | |
| SCHEMBL10695579 | 0.80 | PDE5A (0.57) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21017804 | 0.78 | ACHE (0.52) | ATP4AATP4B | |
| SCHEMBL28027631 | 0.78 | TNKS (0.54) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL7553361 | 0.77 | NPC1 (0.53) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5970052 | 0.73 | TSHR (0.55) | LMNAKDM4EALDH1A1TP53TSHR | |
| SCHEMBL38656506 | 0.73 | PDE5A (0.72) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9320573 | 0.73 | ATP4A (0.74) | ATP4AATP4BNPC1RAB9AKDM4E | |
| SCHEMBL9094859 | 0.72 | HDAC3 (0.68) | ATP4AATP4BNPC1RAB9ALMNA | |
| SCHEMBL20982645 | 0.72 | ACHE (0.46) | ATP4AATP4BNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |