SCHEMBL10695721

SCHEMBL10695721

O=C(CCc1ccc(OCc2ccccc2)cc1)N(O)CCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 13/20 0.80
FFAR1 O14842 5/20 0.67
FFAR4 Q5NUL3 2/20 0.67
LTB4R Q15722 1/20 0.62
LTB4R2 Q9NPC1 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693993 0.89 ALOX5 (1.00) ALOX5FFAR1FFAR4LTB4RLTB4R2
SCHEMBL9374202 0.84 ALOX5 (0.73) ALOX5FFAR1FFAR4LTB4RLTB4R2
SCHEMBL9373373 0.83 ALOX5 (0.71) ALOX5FFAR1FFAR4LTB4RLTB4R2
SCHEMBL10695836 0.83 ALOX5 (0.88) ALOX5FFAR1FFAR4LTB4RLTB4R2
SCHEMBL10692128 0.83 ALOX5 (0.88) ALOX5FFAR1FFAR4LTB4RLTB4R2
SCHEMBL9506981 0.82 ALOX5 (1.00) ALOX5FFAR1FFAR4LTB4RLTB4R2
SCHEMBL10688617 0.81 ALOX5 (1.00) ALOX5FFAR1LTB4RLTB4R2
SCHEMBL10692771 0.81 ALOX5 (1.00) ALOX5FFAR1FFAR4LTB4RLTB4R2
Benzyloxyphenylpropanoic Acid SCHEMBL1134648 0.81 FFAR1 (1.00) FFAR1FFAR4
SCHEMBL1744939 0.81 FFAR1 (1.00) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0196674-A2 Hydroxamates as modulators of arachidonic acid metabolic pathways USV PHARMACEUTICAL CORPORATION (US) 1986-10-08 EP claimed
US-4792560-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS RORER PHARMACEUTICAL CORPORATION (US) 1988-12-20 US disclosed