Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 1.00 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.74 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.74 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695836 | 0.94 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL10692128 | 0.94 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL10692771 | 0.92 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL10695721 | 0.89 | ALOX5 (0.80) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL10692791 | 0.88 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL10689449 | 0.86 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL10695970 | 0.84 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL9374202 | 0.84 | ALOX5 (0.73) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL9373373 | 0.83 | ALOX5 (0.71) | ALOX5LTB4RLTB4R2FFAR1FFAR4 | |
| SCHEMBL14021658 | 0.83 | ALOX5 (0.70) | ALOX5LTB4RLTB4R2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |