Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694539 | 0.98 | SIGMAR1 (0.53) | SIGMAR1HRH3KDM4EALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL7336348 | 0.81 | HRH3 (0.46) | SIGMAR1HRH3KDM4EALDH1A1KCNH2 | |
| SCHEMBL10693219 | 0.81 | HRH3 (0.46) | HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL2109908 | 0.81 | HRH3 (0.46) | SIGMAR1HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL270997 | 0.80 | HRH3 (0.69) | SIGMAR1HRH3KDM4EALDH1A1KCNH2 | |
| SCHEMBL12666600 | 0.80 | HRH3 (0.69) | SIGMAR1HRH3KDM4EALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL5673726 | 0.79 | HRH3 (0.44) | SIGMAR1HRH3KDM4EALDH1A1HRH4 | |
| Hydrochloric Acid SCHEMBL7331038 | 0.79 | ALDH1A1 (0.61) | SIGMAR1HRH3KDM4EALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL7331669 | 0.79 | SIGMAR1 (0.49) | SIGMAR1HRH3ALDH1A1LMNA | |
| SCHEMBL7333053 | 0.79 | SIGMAR1 (0.45) | SIGMAR1HRH3KDM4EALDH1A1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762826-A | FUNGICIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |