SCHEMBL609041

SCHEMBL609041

Fc1cc(C(F)(F)F)cnc1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
TRPA1 O75762 2/20 0.38
POLB P06746 2/20 0.38
KDM4E B2RXH2 2/20 0.38
PLAU P00749 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
AGBL2 Q5U5Z8 1/20 0.38
GAA P10253 2/20 0.36
HTT P42858 2/20 0.36
PDE2A O00408 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695813 0.88 ALDH1A1 (0.49) ALDH1A1POLBKDM4EPLAUSMN1; SMN2
SCHEMBL9256577 0.79 BACE1 (0.32)
SCHEMBL1336778 0.79 ALDH1A1 (0.39) ALDH1A1TRPA1POLBKDM4EPLAU
SCHEMBL12169273 0.79 ALOX5AP (0.41) ALOX5AP
SCHEMBL1498826 0.79 ALDH1A1 (0.43) ALDH1A1TRPA1POLBKDM4EPLAU
SCHEMBL17987938 0.79 AGBL2 (0.49) ALDH1A1POLBKDM4EPLAUSMN1; SMN2
SCHEMBL31153021 0.79 ALDH1A1 (0.39) ALDH1A1TRPA1POLBKDM4EPLAU
SCHEMBL10691786 0.79 ALDH1A1 (0.41) ALDH1A1POLBKDM4EPLAUSMN1; SMN2
SCHEMBL665344 0.77 ALDH1A1 (0.38) ALDH1A1TRPA1POLBKDM4EPLAU
SCHEMBL119201 0.77 ALDH1A1 (0.43) ALDH1A1TRPA1POLBKDM4EPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106499-A1 OREXIN RECEPTOR ANTAGONISTS: 2-AZABICYCLIC COMPOUNDS BIAL - PORTELA & CA., S.A. (PT) 2026-05-21 WO claimed
EP-4688155-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS Bial-Portela & CA, S.A. (PT) 2026-02-11 EP claimed
EP-4688154-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - Portela & Ca., S.A. (PT) 2026-02-11 EP claimed
WO-2025023852-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - PORTELA & CA., S.A. (PT) 2025-01-30 WO claimed
WO-2025023851-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - PORTELA & CA., S.A. (PT) 2025-01-30 WO claimed
CN-114361590-B Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery 松山湖材料实验室 2023-07-25 CN claimed
CN-114361590-A Lithium ion battery electrolyte additive, electrolyte and lithium ion battery 松山湖材料实验室 2022-04-15 CN claimed
EP-0146924-B1 PREPARATION OF DIFLUORPYRIDINE COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1989-06-07 EP claimed
EP-0180864-B1 PREPARATION OF FLUOROPYRIDINES THE DOW CHEMICAL COMPANY (US) 1988-11-30 EP claimed
US-4782161-A HALOGEN EXCHANGE, ACTIVATED CARBON CATALYST THE DOW CHEMICAL COMPANY (US) 1988-11-01 US claimed
EP-0228643-A2 Removal of ferric chloride from halopyridines THE DOW CHEMICAL COMPANY (US) 1987-07-15 EP claimed
US-4649201-A SOLVENT EXTRACTION, ALKYLENE GLYCOL THE DOW CHEMICAL COMPANY (US) 1987-03-10 US claimed
US-4625035-A 2,3-difluoro-5-(trifluoromethyl)pyridine THE DOW CHEMICAL COMPANY (US) 1986-11-25 US claimed
EP-0183228-A2 Chlorine exchange for fluorine in 2-fluoro-pyridine compounds THE DOW CHEMICAL COMPANY (US) 1986-06-04 EP claimed
EP-0180864-A1 Preparation of fluoropyridines THE DOW CHEMICAL COMPANY (US) 1986-05-14 EP claimed
US-4567274-A TRICHLOROMETHYL OR DICHLORFLUOROMETHLPICOLINE THE DOW CHEMICAL COMPANY (US) 1986-01-28 US claimed
US-4563530-A 2,3-DICHLORO- AND 2,3-DIFLUOROPYRIDINES FROM 2-FLUORO-3-CHLOROPYRINES THE DOW CHEMICAL COMPANY (US) 1986-01-07 US claimed
EP-0146924-A2 Preparation of difluorpyridine compounds THE DOW CHEMICAL COMPANY (US) 1985-07-03 EP claimed
US-4480102-A 2,3-Difluoro-5-(trifluoromethyl)pyridine and methods of making and using the same THE DOW CHEMICAL COMPANY (US) 1984-10-30 US claimed
EP-0104715-A2 2,3-Difluoro-5-(trifluoromethyl)pyridine and method of making and using the same THE DOW CHEMICAL COMPANY (US) 1984-04-04 EP claimed