Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696169 | 0.85 | TBXAS1 (0.49) | L3MBTL1TDP1CYP2A6FDPSTBXAS1 | |
| SCHEMBL10695591 | 0.82 | PTAFR (0.48) | KMT2ATBXAS1HTTSMN1; SMN2 | |
| SCHEMBL10694457 | 0.79 | KMT2A (0.46) | KMT2AL3MBTL1TDP1TBXAS1HTT | |
| SCHEMBL3923399 | 0.77 | CYP2A6 (0.59) | L3MBTL1TDP1CYP2A6TBXAS1HRH1 | |
| SCHEMBL10695936 | 0.77 | PTAFR (0.52) | L3MBTL1MAPK1ALDH1A1HTT | |
| SCHEMBL7549229 | 0.76 | TBXAS1 (0.55) | L3MBTL1TDP1CYP2A6TBXAS1HRH1 | |
| SCHEMBL7384270 | 0.76 | TBXAS1 (0.55) | L3MBTL1TDP1CYP2A6TBXAS1HRH1 | |
| SCHEMBL1741940 | 0.75 | TDP1 (0.57) | KMT2AL3MBTL1TDP1FDPSTRPV1 | |
| SCHEMBL7803183 | 0.75 | TDP1 (0.60) | KMT2AL3MBTL1TDP1CYP2A6TBXAS1 | |
| SCHEMBL9522636 | 0.75 | TDP1 (0.60) | KMT2AL3MBTL1TDP1CYP2A6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |