Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 12/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694457 | 0.96 | KMT2A (0.46) | PTAFRKMT2ATBXAS1GAAHTT | |
| SCHEMBL10696517 | 0.92 | KMT2A (0.49) | PTAFRKMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL10695136 | 0.90 | PTAFR (0.51) | PTAFRKMT2ATBXAS1GAA | |
| SCHEMBL10696169 | 0.85 | TBXAS1 (0.49) | TBXAS1 | |
| SCHEMBL10695936 | 0.84 | PTAFR (0.52) | PTAFRHTT | |
| SCHEMBL10695917 | 0.84 | CALM1 (0.47) | KMT2A | |
| SCHEMBL10695814 | 0.82 | MEN1 (0.44) | KMT2ATBXAS1HTTSMN1; SMN2 | |
| SCHEMBL19090372 | 0.82 | TDP1 (0.57) | PTAFRKMT2AGAACRHBPCRHR2 | |
| SCHEMBL10642535 | 0.80 | CA1 (0.57) | PTAFRKMT2ATBXAS1GAAHTT | |
| SCHEMBL28177089 | 0.79 | KMT2A (0.56) | PTAFRKMT2AGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |