Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 13/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695591 | 0.84 | PTAFR (0.48) | PTAFRHTT | |
| SCHEMBL10694457 | 0.81 | KMT2A (0.46) | PTAFRL3MBTL1HTT | |
| SCHEMBL10696169 | 0.79 | TBXAS1 (0.49) | L3MBTL1 | |
| SCHEMBL6160644 | 0.78 | PTAFR (0.49) | PTAFR | |
| SCHEMBL10695814 | 0.77 | MEN1 (0.44) | MAPK1ALDH1A1L3MBTL1HTT | |
| SCHEMBL7167724 | 0.77 | CYP51A1 (0.66) | STAT3MAPK1CYP51A1ALDH1A1NPSR1 | |
| SCHEMBL10772217 | 0.76 | STAT3 (0.65) | STAT3 | |
| SCHEMBL10696517 | 0.76 | KMT2A (0.49) | PTAFRALDH1A1HTT | |
| SCHEMBL6160639 | 0.76 | PTAFR (0.59) | PTAFRMAPK1ALDH1A1NPSR1USP2 | |
| SCHEMBL3923399 | 0.74 | CYP2A6 (0.59) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |