Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434816 | 0.81 | HSD11B1 (0.38) | OPRM1OPRL1HTTSMN1; SMN2 | |
| SCHEMBL891327 | 0.73 | OPRM1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL9000261 | 0.70 | DPP4 (0.36) | ALDH1A1 | |
| SCHEMBL434095 | 0.69 | TSHR (0.43) | OPRM1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL22563669 | 0.68 | POLB (0.40) | MEN1KMT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL10394796 | 0.68 | TDP1 (0.40) | TDP1OPRM1OPRL1SIGMAR1MEN1 | |
| SCHEMBL14720863 | 0.66 | SLC6A3 (0.51) | OPRM1OPRL1SIGMAR1OPRK1CHRM3 | |
| SCHEMBL22530353 | 0.66 | DPP4 (0.33) | ALDH1A1 | |
| SCHEMBL11348505 | 0.66 | TACR1 (0.49) | TACR1 | |
| SCHEMBL435686 | 0.65 | TSHR (0.48) | KMT2AHTTSMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783473-A | ANTICOAGULANTS, VASODILATORS, BRONCHODILATORS | E. R. SQUIBB & SONS, INC. (US) | 1988-11-08 | — | — | US | disclosed |