Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222184 | 1.00 | ADRB3 (0.41) | ADRB3ADRB1CYP4F2CYP4A11PPARA | |
| SCHEMBL200520 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11PPARAALDH1A1RAB9A | |
| SCHEMBL11772230 | 0.82 | CES2 (0.41) | ADRB3ADRB1CYP4F2CYP4A11PPARA | |
| SCHEMBL9144109 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL1988773 | 0.77 | AKR1C3 (0.44) | ALDH1A1KDM4ERAB9AAKR1C2AKR1C1 | |
| SCHEMBL7980315 | 0.76 | ESR1 (0.41) | ADRB3ADRB1PPARAALDH1A1RAB9A | |
| SCHEMBL6511138 | 0.76 | PPARA (0.50) | PPARAALDH1A1KDM4EAKR1C2AKR1C1 | |
| SCHEMBL16034181 | 0.74 | CES2 (0.38) | CYP4F2CYP4A11PPARAALDH1A1CFD | |
| SCHEMBL9724906 | 0.74 | FOLH1 (0.49) | ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL9724910 | 0.74 | FOLH1 (0.49) | ALDH1A1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4776973-A | LIQUID CRYSTAL ELECTROOPTICS DISPLAY DEVICE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-10-11 | — | — | US | disclosed |