Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695315 | 0.84 | SLC18A3 (0.37) | ESR2 | |
| SCHEMBL918249 | 0.84 | SLC2A1 (0.41) | MAP1LC3BHTR1ADRD2DRD1DRD5 | |
| SCHEMBL9810698 | 0.83 | SLC18A3 (0.44) | HCRTR2SMN1; SMN2KMT2A | |
| SCHEMBL15420272 | 0.81 | HCRTR2 (0.40) | HCRTR2 | |
| Formamide SCHEMBL28183255 | 0.80 | KDM1A (0.43) | MAP1LC3BPARP10HTR2AKDM1APTGS1 | |
| SCHEMBL14864487 | 0.80 | NPC1 (0.38) | MAP1LC3BALDH1A1SMN1; SMN2ESR2FAAH | |
| SCHEMBL1066184 | 0.79 | KDM1A (0.48) | MAP1LC3BHTR1ADRD2DRD1DRD5 | |
| SCHEMBL18161913 | 0.79 | KDM1A (0.48) | MAP1LC3BHTR1ADRD2DRD1DRD5 | |
| SCHEMBL9347324 | 0.78 | SLC18A3 (0.45) | ALDH1A1SMN1; SMN2FAAH | |
| Ammonia Solution, Strong SCHEMBL22408764 | 0.77 | KDM1A (0.46) | MAP1LC3BHTR1ADRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272580-A2 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1988-06-29 | — | — | EP | disclosed |
| EP-0102047-B1 | 1-(TRANS-4-ALKYLCYCLOHEXYL)-2-(TRANS-4'-(P-SUBSTITUTED PHENYL)CYCLOHEXYL)ETHANE AND LIQUID CRYSTAL MIXTURE | ASAHI GLASS COMPANY LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4514044-A | 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl) cyclohexyl)ethane and liquid crystal mixture | ASAHI GLASS COMPANY LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0102047-A1 | 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl)cyclohexyl)ethane and liquid crystal mixture | ASAHI GLASS COMPANY LTD. (JP) | 1984-03-07 | — | — | EP | disclosed |