SCHEMBL9810698

SCHEMBL9810698

O=COC1CCC(c2ccccc2)CC1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.44
SIGMAR1 Q99720 1/20 0.44
AKR1C3 P42330 1/20 0.42
AKR1C1 Q04828 1/20 0.42
GRIN2B Q13224 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
IDO1 P14902 2/20 0.37
HCRTR2 O43614 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27263017 0.87 SLC18A3 (0.45) SLC18A3SIGMAR1CYP2D6CYP2C19SMN1; SMN2
SCHEMBL10695866 0.83 MAP1LC3B (0.38) KMT2ASMN1; SMN2HCRTR2
SCHEMBL11664924 0.82 GAA (0.39) SLC18A3SIGMAR1AKR1C3AKR1C1GRIN2B
SCHEMBL10695315 0.81 SLC18A3 (0.37) SLC18A3NPC1RAB9AHPGD
SCHEMBL918249 0.81 SLC2A1 (0.41) SLC18A3MAPTHPGDKMT2ASMN1; SMN2
SCHEMBL8999827 0.81 MRGPRX4 (0.54) RAB9ACYP2C19GAAMAPTSMN1; SMN2
SCHEMBL3303020 0.81 JAK3 (0.54) NPC1RAB9AMAPTKMT2ASMN1; SMN2
SCHEMBL8999825 0.80 PARP10 (0.46) RAB9AGAAMAPTHPGDKMT2A
SCHEMBL27868370 0.79 FFAR4 (0.42) AKR1C3AKR1C1
SCHEMBL14864487 0.78 NPC1 (0.38) SLC18A3NPC1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082289-A 4-R-phenylcyclohexyl formaldehyde ethylene glycol and preparation method thereof 河北凡克新材料有限公司 2023-05-09 CN claimed
JP-1075445-A None JP disclosed
CN-116082289-A 4-R-phenylcyclohexyl formaldehyde ethylene glycol and preparation method thereof 河北凡克新材料有限公司 2023-05-09 CN disclosed
CN-116082289-A 4-R-phenylcyclohexyl formaldehyde ethylene glycol and preparation method thereof 河北凡克新材料有限公司 2023-05-09 CN disclosed
CN-103596431-B Pyrimidine cyclohexyl glucocorticoid receptor modulators 科赛普特治疗公司 2016-06-22 CN disclosed
CN-102241990-B Liquid crystal aligning agent, liquid crystal alignment layer, liquid crystal display element, polyamide acids and polyimides JSR CORP 2014-08-13 CN disclosed
CN-102712719-A Styrene polymer and manufacturing method therefor NIPPON SODA CO 2012-10-03 CN disclosed
CN-102378753-A Plasminogen activator inhibitor-1 inhibitor RENASCIENCE CO LTD 2012-03-14 CN disclosed
CN-102241990-A Liquid crystal aligning agent, liquid crystal alignment layer, liquid crystal display element, polyamide acids and polyimides JSR CORP 2011-11-16 CN disclosed
CN-101815707-A oxadiazole diaryl compounds MERCK SERONO SA 2010-08-25 CN disclosed
CN-1150799-A Benzoheterocyclic derivatives OTSUKA PHARMA CO LTD (JP) 1997-05-28 CN disclosed
CN-1032863-C Copolymer compositions comprising copolymer and one or more lybricating additives SHELL INT RESEARCH (NL) 1996-09-25 CN disclosed
CN-1055375-A The copolymer compositions that contains multipolymer and one or more slip additives SHELL INT RESEARCH (NL) 1991-10-16 CN disclosed
EP-0431613-A2 Process for preparing poly(arylene sulfide sulfone) PHILLIPS PETROLEUM COMPANY (US) 1991-06-12 EP disclosed
US-5013822-A Process for preparing poly(arylene sulfide sulfone) with in-situ preparation of alkali metal carboxylate PHILLIPS PETROLEUM COMPANY (US) 1991-05-07 US disclosed
CN-1012500-B Process for preparing aryl hydroxamates SQUIBB & SONS INC (US) 1991-05-01 CN disclosed
JP-S6475445-A PRODUCTION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID MITSUI TOATSU CHEMICALS 1989-03-22 JP disclosed
EP-0102047-B1 1-(TRANS-4-ALKYLCYCLOHEXYL)-2-(TRANS-4'-(P-SUBSTITUTED PHENYL)CYCLOHEXYL)ETHANE AND LIQUID CRYSTAL MIXTURE ASAHI GLASS COMPANY LTD. (JP) 1986-05-07 EP disclosed
US-4514044-A 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl) cyclohexyl)ethane and liquid crystal mixture ASAHI GLASS COMPANY LTD. (JP) 1985-04-30 US disclosed
EP-0102047-A1 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl)cyclohexyl)ethane and liquid crystal mixture ASAHI GLASS COMPANY LTD. (JP) 1984-03-07 EP disclosed