SCHEMBL15420272

SCHEMBL15420272

O=COC1CCC(c2cc(F)cc(F)c2)CC1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 6/20 0.40
NPY5R Q15761 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695866 0.81 MAP1LC3B (0.38) HCRTR2
SCHEMBL14864493 0.80
SCHEMBL3157843 0.79 NPY5R (0.39) HCRTR2NPY5R
SCHEMBL7851738 0.77 HCRTR2 (0.36) HCRTR2NPY5R
SCHEMBL16210861 0.77 HCRTR2 (0.36) HCRTR2NPY5R
SCHEMBL27956438 0.77 HCRTR2 (0.44) HCRTR2NPY5R
SCHEMBL9810698 0.76 SLC18A3 (0.44) HCRTR2
SCHEMBL16924106 0.73 NPY5R (0.33) HCRTR2NPY5R
SCHEMBL918249 0.73 SLC2A1 (0.41)
SCHEMBL10695315 0.73 SLC18A3 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9605207-B2 Orthoester derivative, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-03-28 US disclosed
EP-2690103-A1 ORTHO ESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2014-01-29 EP disclosed
US-20140021407-A1 ORTHOESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed