Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695866 | 0.80 | MAP1LC3B (0.38) | MAP1LC3BSMN1; SMN2ALDH1A1ESR2FAAH | |
| SCHEMBL10695315 | 0.78 | SLC18A3 (0.37) | NPC1RAB9ASLC18A3ESR2 | |
| SCHEMBL918249 | 0.78 | SLC2A1 (0.41) | MAP1LC3BSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL9810698 | 0.78 | SLC18A3 (0.44) | NPC1RAB9ASMN1; SMN2MAPTSLC18A3 | |
| SCHEMBL13223362 | 0.77 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL1405569 | 0.74 | ESR2 (0.50) | RAB9AMAP1LC3BSMN1; SMN2MAPTLMNA | |
| SCHEMBL4549740 | 0.73 | SLC18A3 (0.41) | RAB9AMAP1LC3BSMN1; SMN2MAPTLMNA | |
| SCHEMBL11280912 | 0.73 | ESR2 (0.59) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL9347324 | 0.73 | SLC18A3 (0.45) | SMN1; SMN2MAPTLMNAALDH1A1SLC18A3 | |
| SCHEMBL15279097 | 0.72 | NPC1 (0.41) | NPC1RAB9AMAP1LC3BSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |