Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13340931 | 0.79 | NOTUM (0.45) | ACHENOTUMKMT2AMEN1MAPT | |
| SCHEMBL14046240 | 0.78 | NOTUM (0.44) | ACHENOTUMKMT2AKDM4EMEN1 | |
| SCHEMBL20178650 | 0.77 | ACHE (0.54) | ACHENOTUMKMT2AKDM4EMEN1 | |
| SCHEMBL5781693 | 0.76 | RAB9A (0.55) | NOTUMKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL5781688 | 0.76 | RAB9A (0.55) | NOTUMKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL12894583 | 0.76 | ALDH1A1 (0.48) | KMT2AKDM4EMEN1MAPTL3MBTL1 | |
| SCHEMBL14156161 | 0.72 | KMT2A (0.46) | ACHENOTUMKMT2AKDM4EMEN1 | |
| SCHEMBL20178648 | 0.72 | SRD5A1 (0.58) | ACHEKDM4EMAPTPOLBALDH1A1 | |
| SCHEMBL10472134 | 0.72 | ACHE (0.45) | ACHENOTUMKMT2AKDM4EMEN1 | |
| SCHEMBL7561228 | 0.71 | DHODH (0.43) | L3MBTL1POLBNFE2L2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |