Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | ADH1C | P00326 | 1/20 | 0.47 |
| ▸ | ADH1A | P07327 | 1/20 | 0.47 |
| ▸ | ADH7 | P40394 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713617 | 0.88 | MAOA (0.64) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL7057730 | 0.86 | MAOA (0.68) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL8812199 | 0.85 | MAOA (0.71) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL10767037 | 0.82 | SIGMAR1 (0.59) | GAAMAPTSIGMAR1DRD4CA12 | |
| SCHEMBL5764 | 0.79 | MEN1 (1.00) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL8831156 | 0.79 | MEN1 (0.64) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL421501 | 0.79 | MEN1 (0.64) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL691630 | 0.78 | MEN1 (0.56) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL6098798 | 0.78 | MEN1 (0.68) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL5040570 | 0.77 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |