Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057730 | 0.94 | MAOA (0.68) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL8812199 | 0.93 | MAOA (0.71) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL10695875 | 0.88 | MEN1 (0.64) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL10768243 | 0.83 | SIGMAR1 (0.66) | SIGMAR1GAAMAPT | |
| SCHEMBL4932707 | 0.81 | MAOA (0.95) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL893154 | 0.81 | MAOA (0.86) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL7621212 | 0.81 | MAOA (0.64) | MAOACHRM2MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9373176 | 0.79 | MAOA (0.62) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL4642587 | 0.79 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL16260102 | 0.79 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106441-A2 | PEPTIDOMIMETICS FOR MODULATING INTERLEUKIN-1 RECEPTOR | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2010-09-23 | — | — | WO | disclosed |
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |