Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540112 | 0.89 | DAO (0.41) | DAOLTB4RALDH1A1TP53KDM4C | |
| SCHEMBL2037474 | 0.84 | LTB4R (0.48) | DAOLTB4RALDH1A1KDM4CTSHR | |
| SCHEMBL8588999 | 0.83 | DAO (0.32) | DAOLTB4RKDM4C | |
| SCHEMBL2033883 | 0.79 | CYP1A2 (0.43) | DAOALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2407624 | 0.78 | DAO (0.44) | DAOALDH1A1KDM4CMAOAGSK3B | |
| SCHEMBL2399697 | 0.77 | DAO (0.47) | DAOLTB4RALDH1A1KDM4CSMN1; SMN2 | |
| SCHEMBL8855371 | 0.77 | DAO (0.42) | DAOLTB4RALDH1A1TP53KDM4C | |
| SCHEMBL81915 | 0.76 | DAO (0.36) | DAOKDM4C | |
| SCHEMBL7354171 | 0.74 | IAPP (0.41) | DAOLTB4RALDH1A1TP53KDM4C | |
| SCHEMBL28318893 | 0.74 | ALDH1A1 (0.38) | DAOALDH1A1TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |