Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037474 | 0.89 | LTB4R (0.48) | DAONPSR1LTB4RKDM4CALDH1A1 | |
| SCHEMBL8855371 | 0.85 | DAO (0.42) | DAONPSR1FFAR1LTB4RKDM4C | |
| SCHEMBL8540112 | 0.83 | DAO (0.41) | DAOFFAR1LTB4RKDM4CALDH1A1 | |
| SCHEMBL7354171 | 0.81 | IAPP (0.41) | DAOFFAR1LTB4RKDM4CALDH1A1 | |
| SCHEMBL3939509 | 0.80 | RPS6KB2 (0.42) | DAOKDM4CALDH1A1 | |
| SCHEMBL1551106 | 0.80 | DAO (0.50) | DAOKDM4CALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL20604279 | 0.78 | LTB4R (0.43) | DAONPSR1FFAR1LTB4RALDH1A1 | |
| SCHEMBL17713714 | 0.78 | DAO (0.48) | DAOKDM4CALDH1A1SMN1; SMN2 | |
| SCHEMBL10796376 | 0.78 | DAO (0.41) | DAOFFAR1LTB4RKDM4CKDM4E | |
| SCHEMBL25250901 | 0.77 | LTB4R (0.49) | DAONPSR1FFAR1LTB4RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542549-B1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2016-05-11 | — | — | EP | disclosed |
| US-9181233-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2015-11-10 | — | — | US | disclosed |
| EP-2542549-A2 | INHIBITORS OF GLUTAMINYL CYCLASE | Probiodrug AG (DE) | 2013-01-09 | — | — | EP | disclosed |
| US-20110224259-A1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2011-09-15 | — | — | US | disclosed |
| WO-2011107530-A2 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2011-09-09 | — | — | WO | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-5414108-A | From a Meldrum's acid derivative | BIOGAL GYOGYSZERGRAR (HU) | 1995-05-09 | — | — | US | disclosed |
| US-5350872-A | Decyclization and decarboxylation of a 1,3-dioxane-4,6-dione | BIOGAL GYOGYSZERGRAR (HU) | 1994-09-27 | — | — | US | disclosed |
| EP-0578850-A1 | Process for the preparation of carboxylic acids and derivatives of them | BIOGAL GYOGYSZERGYAR (HU) | 1994-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224259-A1 | NOVEL INHIBITORS | QPCT, GLUL, GLS | DAO 60/4885NPSR1 4211/4885FFAR1 3916/4885 |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | DAO 1438/4885NPSR1 3344/4885FFAR1 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.