SCHEMBL10695933

SCHEMBL10695933

O=C(O)c1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.57
HNF4A P41235 3/20 0.56
AKR1C2 P52895 4/20 0.54
AKR1C1 Q04828 4/20 0.54
AKR1C3 P42330 2/20 0.54
PTPN6 P29350 3/20 0.53
PTPN2 P17706 2/20 0.53
AKR1C4 P17516 1/20 0.44
HK2 P52789 1/20 0.43
ACMSD Q8TDX5 3/20 0.43
DHFR P00374 1/20 0.43
MCL1 Q07820 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
FOLH1 Q04609 1/20 0.41
PDE4B Q07343 1/20 0.41
BACE1 P56817 1/20 0.41
FABP3 P05413 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50362 0.86 HNF4A (0.50) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL5712228 0.83 PTPN1 (0.57) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL8350739 0.81 PTPN1 (0.56) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL830012 0.81 ALDH1A1 (0.48) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
Hydrochloric Acid SCHEMBL29011347 0.80 ALDH1A1 (0.46) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL29046909 0.79 ACMSD (0.50) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL8459682 0.79 HNF4A (0.50) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL29443090 0.79 HNF4A (0.50) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
Benzene SCHEMBL3625753 0.78 PTPN1 (0.50) PTPN1HNF4AAKR1C2AKR1C1AKR1C3
SCHEMBL6842109 0.78 PTPN1 (0.70) PTPN1HNF4AAKR1C2AKR1C1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234515-B Recording material and recording sheet 日本曹达株式会社 2022-02-11 CN disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
CN-109641472-B Recording material and recording sheet 日本曹达株式会社 2021-07-27 CN disclosed
CN-110709255-A Recording material and compound 日本曹达株式会社 2020-01-17 CN disclosed
US-4727162-A COLOR FORMERS FOR HEAT OR PRESSURE RECORDING MATERIAL SHIN NISSO KAKO CO., LTD. (JP) 1988-02-23 US disclosed
US-4695640-A COLOR FORMER FOR RECORDING MATERIALS SHIN NISSO KAKO CO., LTD. (JP) 1987-09-22 US disclosed