Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20363128 | 0.84 | ALDH1A1 (0.61) | MEN1KMT2ANPC1RAB9ALTB4R2 | |
| SCHEMBL10693562 | 0.81 | MEN1 (0.56) | MEN1KMT2AALOX5NPC1RAB9A | |
| SCHEMBL10693228 | 0.79 | KMT2A (0.62) | MEN1KMT2AALOX5NPC1RAB9A | |
| SCHEMBL10695487 | 0.79 | NPC1 (0.50) | MEN1KMT2AALOX5NPC1RAB9A | |
| SCHEMBL10991682 | 0.78 | MEN1 (0.60) | MEN1KMT2AALOX5NPC1RAB9A | |
| SCHEMBL29176461 | 0.78 | OPRM1 (0.59) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL22160774 | 0.77 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL22312249 | 0.76 | KMT2A (0.52) | MEN1KMT2ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16061331 | 0.76 | TP53 (0.56) | MEN1KMT2AALOX5NPC1RAB9A | |
| SCHEMBL2718571 | 0.75 | TRPM8 (0.62) | TP53TDP1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |