Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411356 | 0.81 | HRH3 (0.77) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL10695952 | 0.79 | MAPT (0.48) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL7681948 | 0.77 | HRH3 (0.75) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL7676624 | 0.76 | HRH3 (0.49) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL103116 | 0.76 | RAB9A (0.61) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL7675257 | 0.76 | HRH3 (0.73) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL10674445 | 0.73 | HRH3 (0.71) | HRH3 | |
| SCHEMBL19914857 | 0.71 | MAPT (0.58) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL10674439 | 0.71 | HRH3 (0.50) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL9570481 | 0.70 | RAB9A (0.61) | RAB9AMAPTNPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791117-A | LOCAL ANTESTHETICS, ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |