SCHEMBL10696199

SCHEMBL10696199

CCCCCCCCNc1ncnc(Cl)n1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
DNM2 P50570 11/20 0.46
NPSR1 Q6W5P4 2/20 0.43
S1PR2 O95136 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KCNH3 Q9ULD8 2/20 0.43
CCNB2 O95067 1/20 0.40
CDK1 P06493 1/20 0.40
CCNB1 P14635 1/20 0.40
CCNB3 Q8WWL7 1/20 0.40
ABL1 P00519 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29720560 1.00 KMT2A (0.58) KMT2ADNM2NPSR1S1PR2LMNA
SCHEMBL2514104 0.98 KMT2A (0.55) KMT2ADNM2NPSR1S1PR2LMNA
SCHEMBL6643508 0.93 KMT2A (0.49) KMT2ADNM2NPSR1LMNASMN1; SMN2
SCHEMBL6270062 0.86 KMT2A (0.50) KMT2ALMNASMN1; SMN2MAPTHTT
SCHEMBL516082 0.86 KCNH3 (0.54) KMT2ADNM2NPSR1S1PR2LMNA
Ammonia Solution, Strong SCHEMBL15720632 0.84 KMT2A (0.53) KMT2ALMNAMAPTHTT
SCHEMBL7937257 0.80 KMT2A (0.77) KMT2ADNM2LMNAKCNH3
SCHEMBL10912439 0.80 KMT2A (0.77) KMT2ADNM2LMNAKCNH3
SCHEMBL11787843 0.80 KMT2A (0.83) KMT2ADNM2NPSR1LMNAKCNH3
SCHEMBL1562316 0.80 KMT2A (0.77) KMT2ADNM2LMNAKCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273011-A2 N,N-bis(hydroxyethyl)hydroxylamine ester stabilizers CIBA-GEIGY AG (CH) 1988-06-29 EP disclosed