SCHEMBL516082

SCHEMBL516082

CCCCCNc1ncnc(NCCCCC)n1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 2/20 0.54
KMT2A Q03164 1/20 0.50
DNM2 P50570 9/20 0.49
NPSR1 Q6W5P4 2/20 0.46
S1PR2 O95136 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CCNB2 O95067 2/20 0.45
CDK1 P06493 2/20 0.45
CCNB1 P14635 2/20 0.45
CCNB3 Q8WWL7 2/20 0.45
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
HRH4 Q9H3N8 1/20 0.43
HCAR3 P49019 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2814764 0.87 SMN1; SMN2 (0.50) KCNH3KMT2ADNM2NPSR1S1PR2
SCHEMBL11173788 0.87 KCNH3 (0.44) KCNH3KMT2ADNM2NPSR1S1PR2
SCHEMBL2514104 0.87 KMT2A (0.55) KCNH3KMT2ADNM2NPSR1S1PR2
SCHEMBL29720560 0.86 KMT2A (0.58) KCNH3KMT2ADNM2NPSR1S1PR2
SCHEMBL10696199 0.86 KMT2A (0.58) KCNH3KMT2ADNM2NPSR1S1PR2
SCHEMBL8618089 0.86 SMN1; SMN2 (0.49) KCNH3KMT2ADNM2NPSR1S1PR2
SCHEMBL10572863 0.85 HRH4 (0.42) KCNH3KMT2ADNM2NPSR1HRH4
SCHEMBL30428026 0.85 CYP1A2 (0.47) KCNH3KMT2ALMNASMN1; SMN2HTT
SCHEMBL514975 0.84 KCNH3 (0.63) KCNH3KMT2ADNM2NPSR1MAPT
SCHEMBL11306494 0.84 HCAR3 (0.46) KCNH3KMT2ADNM2NPSR1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120027698-A9 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2012-02-02 US claimed
US-20100278764-A1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2010-11-04 US claimed
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process L'OREAL S.A. (FR) 2007-11-15 US claimed
US-20070189991-A1 Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment L'OREAL S.A. (FR) 2007-08-16 US claimed
EP-1797868-A1 Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
EP-1797867-A1 Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
US-6500606-B2 USEFUL FOR PROVIDING COLOR POSITIVE IMAGES IN COLOR REVERSAL PHOTOGRAPHIC MATERIALS EASTMAN KODAK COMPANY 2002-12-31 US claimed
US-20020182548-A1 Photographic processing compositions and methods of using in color reversal image formation EASTMAN KODAK COMPANY 2002-12-05 US claimed
EP-1231505-A2 Photographic processing compositions and methods of using thereof in color reversal image formation EASTMAN KODAK COMPANY (US) 2002-08-14 EP claimed
US-6395461-B1 BLEACHING, FIXING EASTMAN KODAK COMPANY 2002-05-28 US claimed
US-6395462-B2 A SPECTRAL SENSITIZING DYE STAIN REDUCING AGENT THAT IS A COLORLESS OR SLIGHTLY YELLOW COMPOUND HAVING AN EXTENDED PLANAR PI SYSTEM, DEVOID OF DIAMINOSTILBENE FRAMENT OR FUSED TRIAZOLE NUCLEUS, IS 2,6 DIARYLAMINOTRIAZINE COMPOUND GOSWAMI RAMANUJ (US) 2002-05-28 US claimed
US-20010004514-A1 Photographic processing compositions containing stain reducing agent GOSWAMI RAMANUJ (US) 2001-06-21 US claimed
EP-1109063-A1 Photographic processing methods using compositions containing stain reducing agent EASTMAN KODAK COMPANY (US) 2001-06-20 EP claimed
US-6232053-B1 COLORLESS OR SLIGHTLY YELLOW COMPOUND HAVING AN EXTENDED PLANAR PI SYSTEM, THAT IS DEVOID OF A DIAMINOSTILBENE FRAGMENT OR FUSED TRIAZOLE NUCLEUS, BUT THAT HAS A SOLUBILITY OF AT LEAST 5X10(5) IN WATER AT ROOM TEMPERATURE. EASTMAN KODAK COMPANY 2001-05-15 US claimed
US-6232052-B1 COLORLESS OR SLIGHTLY YELLOW COMPOUND HAVING AN EXTENDED PLANAR PI SYSTEM, THAT IS DEVOID OF A DIAMINOSTILBENE FRAGMENT OR FUSED TRIAZOLE NUCLEUS, BUT THAT HAS A SOLUBILITY OF AT LEAST 0.05 MOL/L IN WATER AT ROOM TEMPERATURE. EASTMAN KODAK COMPANY 2001-05-15 US claimed
US-6153364-A USING 2,6-DIARYLAMINOTRIAZINE EASTMAN KODAK COMPANY (US) 2000-11-28 US claimed
US-6153365-A FIXING MIXTURE CONTAINING DYE REDUCING AGENT EASTMAN KODAK COMPANY (US) 2000-11-28 US claimed
EP-3548544-B1 AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS OREAL (FR) 2021-07-21 EP disclosed
US-6153364-A USING 2,6-DIARYLAMINOTRIAZINE EASTMAN KODAK COMPANY (US) 2000-11-28 US disclosed
US-6153365-A FIXING MIXTURE CONTAINING DYE REDUCING AGENT EASTMAN KODAK COMPANY (US) 2000-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070189991-A1 Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment KRT18, TST, CTH KCNH3 2953/4885KMT2A 3276/4885DNM2 4599/4885
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process KRT18, DSG1, DSC1 KCNH3 548/4885KMT2A 2513/4885DNM2 2766/4885
US-20120027698-A9 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, DSC1 KCNH3 574/4885KMT2A 2705/4885DNM2 2700/4885
US-20100278764-A1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, DSC1 KCNH3 574/4885KMT2A 2705/4885DNM2 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.