Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20512341 | 0.84 | TBXAS1 (0.49) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL9748629 | 0.81 | CYP19A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28198916 | 0.78 | CYP19A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11624611 | 0.78 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL6965526 | 0.78 | CYP19A1 (0.70) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11700934 | 0.77 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11624547 | 0.77 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11260679 | 0.76 | ADRA2C (0.71) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11703338 | 0.76 | TBXAS1 (0.55) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL11706400 | 0.76 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392326-B1 | Dichloro-substituted imidazole derivatives as antifungal agents | ESPANOLA FARMA THERAPEUT (ES) | 1994-07-20 | — | — | EP | disclosed |
| US-5177099-A | Dichloro-substituted imidazole derivatives as antifungal agents | SOCIEDAD ESPANOLA DE ESPECIALIDADES FARMACO-TERAPEUTICAS S.A. (ES) | 1993-01-05 | — | — | US | disclosed |
| EP-0392326-A1 | Dichloro-substituted imidazole derivatives as antifungal agents | SOCIEDAD ESPANOLA DE ESPECIALIDADES FARMACO-TERAPEUTICAS, S.A. (ES) | 1990-10-17 | — | — | EP | disclosed |