Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357449 | 0.75 | SIGMAR1 (0.58) | SIGMAR1HTR2CALDH1A1LMNA | |
| SCHEMBL10699144 | 0.72 | CHRM2 (0.41) | — | |
| SCHEMBL10697885 | 0.72 | ABL1 (0.48) | ALDH1A1LMNAHTT | |
| SCHEMBL31704506 | 0.72 | QDPR (0.36) | SIGMAR1HTR2CHRH3QDPRALDH1A1 | |
| SCHEMBL31706419 | 0.72 | QDPR (0.36) | SIGMAR1HTR2CHRH3QDPRALDH1A1 | |
| Bromide SCHEMBL10698646 | 0.71 | ABL1 (0.47) | ALDH1A1LMNAHTT | |
| SCHEMBL7940586 | 0.71 | SIGMAR1 (0.49) | SIGMAR1HTR2CHRH3QDPRALDH1A1 | |
| Hydrochloric Acid SCHEMBL10697142 | 0.71 | CHRM2 (0.40) | — | |
| SCHEMBL24107845 | 0.70 | MAPT (0.41) | ALDH1A1LMNA | |
| SCHEMBL2358010 | 0.69 | SIGMAR1 (0.58) | SIGMAR1HTR2CQDPRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |