Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10698646 | 0.99 | ABL1 (0.47) | ABL1NPC1HSD17B10KDM4EMAPK1 | |
| Bromide SCHEMBL10697998 | 0.78 | ABL1 (0.47) | ABL1NPC1HSD17B10KDM4EMAPK1 | |
| SCHEMBL31704506 | 0.76 | QDPR (0.36) | MAPK1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31706419 | 0.76 | QDPR (0.36) | MAPK1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10696282 | 0.72 | SIGMAR1 (0.42) | LMNAALDH1A1HTT | |
| SCHEMBL14544114 | 0.71 | WNT3A (0.57) | KDM4E | |
| SCHEMBL10698628 | 0.71 | ABL1 (0.45) | ABL1NPC1HSD17B10KDM4EMAPK1 | |
| SCHEMBL10697725 | 0.69 | SMN1; SMN2 (0.43) | ABL1NPC1HSD17B10KDM4EMAPK1 | |
| SCHEMBL13842881 | 0.69 | ABL1 (0.51) | ABL1NPC1HSD17B10KDM4EMAPK1 | |
| SCHEMBL11350463 | 0.68 | L3MBTL1 (0.62) | ABL1NPC1HSD17B10KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |