Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699085 | 0.94 | MEN1 (0.37) | CA1CA9LMNAMEN1KMT2A | |
| SCHEMBL12615012 | 0.93 | — | — | |
| SCHEMBL27840603 | 0.90 | CCR5 (0.36) | CA1CA9LMNAMEN1KMT2A | |
| SCHEMBL10696277 | 0.87 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL10698398 | 0.86 | — | — | |
| SCHEMBL1383985 | 0.86 | — | — | |
| SCHEMBL16597953 | 0.79 | — | — | |
| SCHEMBL2868810 | 0.77 | TSHR (0.38) | LMNAKDM4EALDH1A1 | |
| SCHEMBL5597049 | 0.77 | TSHR (0.38) | LMNAKDM4EALDH1A1 | |
| SCHEMBL449800 | 0.77 | TSHR (0.38) | LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253767-A1 | Parasiticide and insecticide | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | claimed |
| EP-0253767-A1 | Parasiticide and insecticide | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | disclosed |