Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | RNF4 | P78317 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10315613 | 0.87 | MTNR1B (0.73) | SMN1; SMN2HPGDRNF4MTNR1BMAPK1 | |
| SCHEMBL2516508 | 0.84 | ALDH1A1 (0.67) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL5662256 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2HPGDRNF4MTNR1BMAPK1 | |
| SCHEMBL5662258 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2HPGDRNF4MTNR1BMAPK1 | |
| SCHEMBL11642853 | 0.84 | XIAP (0.70) | SMN1; SMN2HPGDRNF4MTNR1BMAPK1 | |
| Water SCHEMBL27691964 | 0.83 | ALDH1A1 (0.65) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL3683038 | 0.82 | MAPT (0.53) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL11760683 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDMTNR1BMAPK1PGR | |
| SCHEMBL12329947 | 0.81 | NPY5R (0.64) | SMN1; SMN2HPGDRNF4MTNR1BMAPK1 | |
| SCHEMBL2610080 | 0.80 | KMT2A (0.65) | SMN1; SMN2HPGDNPY5RCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255178-A2 | Process for preparing hetero aryl and aryl alkanoic acids | Nobel Chemicals AB (SE) | 1988-02-03 | — | — | EP | disclosed |