Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198393 | 0.70 | AHR (0.43) | MTNR1AAHRMAOAMAOBALOX5 | |
| SCHEMBL10637475 | 0.70 | MTNR1A (0.40) | MTNR1AAHRMAOAMAOBALOX5 | |
| SCHEMBL17577921 | 0.70 | MTNR1A (0.40) | MTNR1AAHRMAOAMAOBALOX5 | |
| SCHEMBL6437548 | 0.70 | AHR (0.46) | MTNR1AAHRMAOAMAOBALOX5 | |
| SCHEMBL4976768 | 0.70 | MTNR1A (0.36) | MTNR1AAHRMAOAMAOBALOX5 | |
| SCHEMBL23633181 | 0.68 | MTNR1A (0.35) | MTNR1AAHRMAOAMAOBALOX5 | |
| SCHEMBL6483538 | 0.68 | MTNR1A (0.39) | MTNR1AAHRMAOAMAOBALOX5 | |
| Ethylene SCHEMBL28076033 | 0.68 | — | — | |
| SCHEMBL3102452 | 0.67 | MAOA (0.56) | AHRMAOAMAOBALOX5ABCG2 | |
| SCHEMBL8668546 | 0.67 | MAOA (0.56) | AHRMAOAMAOBALOX5ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284752-A1 | Oxime ethers of 2,6-dioxabicyclo[3.3.0]octanones | Heinrich Mack Nachf. (DE) | 1988-10-05 | — | — | EP | claimed |
| EP-0284752-A1 | Oxime ethers of 2,6-dioxabicyclo[3.3.0]octanones | Heinrich Mack Nachf. (DE) | 1988-10-05 | — | — | EP | disclosed |
| EP-0106860-A1 | NEW CARBOXAMIDOGUANIDINS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | BOUCHARA EMILE (FR) | 1984-05-02 | — | — | EP | disclosed |
| WO-1983003829-A1 | NEW CARBOXAMIDOGUANIDINS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOUCHARA, EMILE (FR) | 1983-11-10 | — | — | WO | disclosed |