Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813287 | 0.84 | TSHR (0.44) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL9224894 | 0.78 | CRHBP (0.43) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL9523478 | 0.76 | KDM4E (0.47) | KDM4EMEN1KMT2ACYP2C19 | |
| SCHEMBL10815571 | 0.76 | KMT2A (0.51) | ESR1ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL9227528 | 0.73 | CRHBP (0.44) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL10626256 | 0.72 | CRHBP (0.39) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL9875296 | 0.71 | CRHBP (0.60) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL32684616 | 0.71 | CRHBP (0.56) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL10813398 | 0.71 | ESR1 (0.42) | ESR1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL7019908 | 0.70 | CRHBP (0.58) | CRHBPCRHR2ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0153709-A2 | Novel cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |