Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095748 | 0.81 | KDM4E (0.53) | KDM4ESMN1; SMN2GAAPOLBKMT2A | |
| SCHEMBL10815571 | 0.78 | KMT2A (0.51) | KDM4EKMT2ATSHRMEN1 | |
| SCHEMBL10813398 | 0.77 | ESR1 (0.42) | KDM4ESMN1; SMN2CYP2C19KMT2ATSHR | |
| SCHEMBL10696541 | 0.76 | CRHBP (0.43) | KDM4ECYP2C19KMT2AMEN1 | |
| SCHEMBL28590805 | 0.75 | KDM4E (0.46) | KDM4ESMN1; SMN2GAAPOLBCYP1A2 | |
| SCHEMBL1664069 | 0.72 | MEN1 (0.46) | KDM4ESMN1; SMN2GAAPOLBKMT2A | |
| SCHEMBL17113282 | 0.71 | KDM4E (0.42) | KDM4ESMN1; SMN2GAAPOLBKMT2A | |
| SCHEMBL9609770 | 0.71 | KDM4E (0.50) | KDM4ESMN1; SMN2GAAPOLBKMT2A | |
| SCHEMBL28625554 | 0.71 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2GAAPOLBCYP1A2 | |
| SCHEMBL8102665 | 0.71 | KDM4E (0.50) | KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112987-B1 | IMIDAZOLYLALKYLTHIENYL-TETRAHYDROPYRIDAZINES AND PROCESS FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1987-04-01 | — | — | EP | claimed |
| EP-0282365-B1 | 1-DETHIA-2-THIA-CEPHALOSPORANIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-05-12 | — | — | EP | disclosed |
| US-4908359-A | Pharmaceuticals | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |
| EP-0282365-A1 | 1-Dethia-2-thia-cephalosporanic-acid derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1988-09-14 | — | — | EP | disclosed |
| EP-0069872-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |
| US-4495182-A | TREATMENT OF INFECTIOUS DISEASES;CEPHALOSPORINS AND DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-22 | — | — | US | disclosed |
| EP-0069872-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-19 | — | — | EP | disclosed |