Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697364 | 0.81 | HTR2C (0.44) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL10696756 | 0.81 | MEN1 (0.46) | ALDH1A1KDM4EGAAMEN1MAPT | |
| Trimethylammonium SCHEMBL10700655 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL10696361 | 0.78 | NQO2 (0.42) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL9756250 | 0.72 | NR4A2 (0.43) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL13083665 | 0.71 | GAA (0.50) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL27554482 | 0.69 | NR4A2 (0.41) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL3560986 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL13555146 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL152993 | 0.69 | NR4A2 (0.59) | ALDH1A1KDM4EGAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |