Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR1D | P28221 | 4/20 | 0.40 |
| ▸ | HTR1B | P28222 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696361 | 0.83 | NQO2 (0.42) | GAANPSR1HTR2AMAPTMEN1 | |
| SCHEMBL10696756 | 0.82 | MEN1 (0.46) | HTR2CGAANPSR1HTR2AMAPT | |
| Trimethylammonium SCHEMBL10700655 | 0.81 | ALDH1A1 (0.39) | HTR2CGAANPSR1HTR2AMAPT | |
| Iodide SCHEMBL10696547 | 0.81 | ALDH1A1 (0.39) | GAANPSR1HTR2AMAPTMEN1 | |
| SCHEMBL13083665 | 0.75 | GAA (0.50) | GAANPSR1HTR2AMAPTMEN1 | |
| SCHEMBL9756250 | 0.73 | NR4A2 (0.43) | GAANPSR1MAPTMEN1KMT2A | |
| SCHEMBL2461799 | 0.73 | KDM4E (0.60) | HTR2CGAANPSR1HTR2AMAPT | |
| SCHEMBL27554482 | 0.70 | NR4A2 (0.41) | GAANPSR1MAPTMEN1KMT2A | |
| SCHEMBL13555146 | 0.69 | ALDH1A1 (0.48) | HTR2CGAANPSR1HTR2AMAPT | |
| SCHEMBL3560986 | 0.69 | ALDH1A1 (0.48) | GAANPSR1HTR2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |