Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 13/20 | 0.61 |
| ▸ | BACE1 | P56817 | 13/20 | 0.61 |
| ▸ | BCHE | P06276 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770315 | 0.96 | CARM1 (0.60) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL18658247 | 0.82 | CARM1 (0.70) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL20492896 | 0.81 | CARM1 (0.68) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL5272937 | 0.80 | ACHE (0.71) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL20492895 | 0.80 | CARM1 (0.67) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL4499743 | 0.79 | CARM1 (0.74) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL17102128 | 0.78 | CARM1 (0.65) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL14367985 | 0.76 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL5544531 | 0.75 | SIGMAR1 (0.73) | — | |
| SCHEMBL20492650 | 0.75 | CARM1 (0.64) | CARM1PRMT6ACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |