Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.65 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.65 |
| ▸ | ACHE | P22303 | 11/20 | 0.61 |
| ▸ | BACE1 | P56817 | 11/20 | 0.61 |
| ▸ | BCHE | P06276 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12672171 | 0.88 | HRH3 (0.55) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL18658247 | 0.85 | CARM1 (0.70) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL20492896 | 0.83 | CARM1 (0.68) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL20492895 | 0.82 | CARM1 (0.67) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL4499743 | 0.81 | CARM1 (0.74) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL7809990 | 0.81 | HRH3 (0.66) | CARM1PRMT6ACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL8055639 | 0.80 | HRH3 (0.65) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL5272937 | 0.80 | ACHE (0.71) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL13229777 | 0.79 | SIGMAR1 (0.74) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL10696583 | 0.78 | CARM1 (0.61) | CARM1PRMT6ACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539133-B | Method for preparing prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-117050003-A | Preparation method of 1- (3-methoxypropyl) -4-piperidinamine | 山东新时代药业有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-115703733-A | Preparation method of prucalopride intermediate | 山东新时代药业有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115197123-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 山东新时代药业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114591220-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114539133-A | Method for preparing prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539134-A | Synthetic method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2015139332-A1 | METHOD FOR SYNTHESIZING N-(3-METHOXYLPROPYL)-4-AMINOPIPERIDINE | 悦康药业集团有限公司 | 2015-09-24 | — | — | WO | disclosed |